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Mark D Fleming Selected Research

Hypoxia (Hypoxemia)

2/2013The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption.
1/2008The regulation of hepcidin and its effects on systemic and cellular iron metabolism.

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Mark D Fleming Research Topics

Disease

27Anemia
02/2024 - 11/2002
16Iron Overload
01/2021 - 08/2005
15Sideroblastic Anemia
02/2024 - 10/2002
15Iron Deficiencies
12/2021 - 10/2005
11Neoplasms (Cancer)
01/2017 - 12/2006
9Hemochromatosis (Bronze Diabetes)
01/2021 - 08/2005
8Thalassemia
01/2021 - 11/2004
7beta-Thalassemia (Cooley's Anemia)
01/2021 - 11/2004
6hypochromic microcytic Anemia
06/2012 - 11/2005
5VLCAD deficiency
12/2023 - 10/2002
5Iron-Deficiency Anemia (Anemia, Iron Deficiency)
10/2019 - 11/2005
4Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/2023 - 06/2011
4Chronic Disease (Chronic Diseases)
01/2021 - 11/2002
4X-linked sideroblastic anemia
10/2016 - 10/2002
4Inflammation (Inflammations)
01/2016 - 02/2006
3Megaloblastic Anemia
02/2024 - 10/2002
3Erythropoietic Protoporphyria
01/2021 - 06/2005
3Leukemia
01/2019 - 06/2011
3Abdominal Aortic Aneurysm
01/2017 - 04/2015
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
08/2015 - 10/2013
3Lymphoma (Lymphomas)
09/2014 - 09/2007
3type 2 Hemochromatosis
02/2012 - 10/2004
2Bone Marrow Failure Disorders
11/2022 - 07/2013
2Hemolytic Anemia
01/2022 - 08/2005
2Hemolysis
06/2018 - 08/2005
2Splenomegaly
06/2018 - 01/2016
2Pain (Aches)
01/2017 - 08/2015
2Wounds and Injuries (Trauma)
01/2017 - 10/2014
2Refractory Anemia
12/2016 - 11/2002
2Aneurysm (Aneurysms)
08/2015 - 01/2015
2Thrombosis (Thrombus)
08/2015 - 09/2009
2Iron-Refractory Iron Deficiency Anemia
02/2015 - 05/2010
2Ewing Sarcoma (Sarcoma, Ewing)
11/2014 - 05/2013
2Hypoxia (Hypoxemia)
02/2013 - 01/2008
2Ataxia (Dyssynergia)
04/2007 - 10/2002
1Rare Diseases (Rare Disease)
02/2024
1COVID-19
09/2023
1Neurodevelopmental Disorders
11/2022
1Rhabdomyolysis
01/2022
1Hemorrhage
01/2022
1Fever (Fevers)
01/2022
1Triosephosphate Isomerase Deficiency
01/2022
1Virus Diseases (Viral Diseases)
12/2021
1Infections
12/2021
1Pneumonia (Pneumonitis)
12/2021
1Aortic Aneurysm (Aneurysm, Aortic)
07/2020
1Ischemia
07/2020

Drug/Important Bio-Agent (IBA)

48IronIBA
02/2024 - 10/2002
25HepcidinsIBA
12/2021 - 11/2002
16Proteins (Proteins, Gene)FDA Link
10/2020 - 10/2004
9Heme (Haem)IBA
11/2019 - 10/2002
7Small Interfering RNA (siRNA)IBA
01/2021 - 03/2008
6Hormones (Hormone)IBA
01/2021 - 05/2008
5GlobinsIBA
01/2021 - 11/2005
5Hemoglobins (Hemoglobin)IBA
11/2019 - 11/2005
5Transferrin (beta 2 Transferrin)IBA
01/2016 - 11/2005
4Mitochondrial DNA (mtDNA)IBA
02/2024 - 02/2010
4Transferrin Receptors (Transferrin Receptor)IBA
01/2021 - 04/2013
4SulfurIBA
10/2020 - 10/2002
3zinc protoporphyrinIBA
11/2019 - 11/2005
3Biomarkers (Surrogate Marker)IBA
01/2016 - 07/2010
3Peptide Hormones (Polypeptide Hormones)IBA
11/2011 - 08/2005
2C-Reactive ProteinIBA
02/2024 - 01/2020
2DiamondIBA
11/2022 - 11/2017
2Ferrochelatase (Heme Synthetase)IBA
01/2021 - 01/2020
2Testosterone (Sustanon)FDA Link
01/2020 - 01/2016
2ErythropoietinFDA Link
01/2020 - 01/2016
2Serine Proteases (Serine Protease)IBA
10/2019 - 05/2008
2Ferritins (Ferritin)IBA
01/2019 - 06/2011
2Tyrosine (L-Tyrosine)FDA Link
01/2018 - 05/2013
2sulfated polyvinyl alcoholIBA
08/2015 - 01/2015
2EnzymesIBA
02/2015 - 03/2008
2Phosphotransferases (Kinase)IBA
05/2013 - 06/2005
2Messenger RNA (mRNA)IBA
05/2010 - 11/2002
2Protein Isoforms (Isoforms)IBA
03/2008 - 08/2005
2AntigensIBA
09/2007 - 11/2005
2AntioxidantsIBA
11/2004 - 10/2004
2Thiamine (Aneurin)FDA Link
09/2003 - 10/2002
1Protein Glutamine gamma Glutamyltransferase 2IBA
02/2024
1Folic Acid (Vitamin M)FDA LinkGeneric
02/2024
1COVID-19 VaccinesIBA
09/2023
1ElementsIBA
11/2022
1PhosphofructokinasesIBA
01/2022
1Phosphoglycerate Kinase (Kinase, Phosphoglycerate)IBA
01/2022
1Fructose-Bisphosphate Aldolase (Aldolase)IBA
01/2022
1VaccinesIBA
12/2021
1MicronutrientsIBA
12/2021
1Neutralizing AntibodiesIBA
12/2021
1ProteomeIBA
11/2021

Therapy/Procedure

13Therapeutics
03/2020 - 11/2004
4Transplantation
12/2023 - 11/2008
3RNAi Therapeutics
01/2020 - 02/2013
3Surgical Amputation (Amputations)
11/2018 - 08/2016
3Endovascular Aneurysm Repair
01/2017 - 04/2015
2Stem Cell Transplantation
03/2020 - 06/2011
2Drug Therapy (Chemotherapy)
03/2020 - 09/2014
2Injections
01/2016 - 01/2011
1Ligation
02/2024
1Ambulatory Care (Outpatient Care)
01/2021
1Replantation
07/2020